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Iberoamerican Journal of Medicine

Iberoamerican Journal of Medicine (Iberoam J Med) (ISSN: 2695-5075) is a peer-reviewed open-access international journal without any submission and publication fees. Iberoamerican Journal of Medicine publishes interesting original research conducted in all fields of medicine, interesting case reports and clinical images, reviews, editorials, letters, comments and letters to the Editor including reports on publication and research ethics. Iberoamerican Journal of Medicine encourages and enables a...



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This case report presents a lipofibromatous hamartoma of the median nerve in a 31-year-old man who presents local deformity and a sensory deficit in the nerve territory. The tumor was evaluated with magnetic resonance, computed tomography, and plain film radiography, studying the pathognomonic findings of this tumor. The patient did not want surgical treatment because of prior surgical sequelae. A prior surgical biopsy was reported as a peripheral nerve with normal axonal fascicles surrounded...
Topics: Lipofibromatous hamartoma, Median nerve, Carpal tunnel, Magnetic resonance, Macrodactyly
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Introduction : Urinary Tract infection (UTI) is considered as the most common infections disease among women. UTI may lead to a serious complication in both kidneys. In this study, we tried to determine whether the alternation in platelet count during UTI is related to specific Gram-type of bacteria causing the infection. This assists the medical staff in selection of suitable antimicrobial drug. Material and Methods : Data of all urine cultures from Gynecology Department/ Albaraa...
Topics: Urinary tract infection, Women, Platelet count, Bacteria, Gram-type
Objective : This article aims to explore the role and responsibility of physicians in the era of social media; the authors take as an example of the current pandemic of Coronavirus disease 2019 (COVID-19). Also, we highlight how social media impact the way populations trust and follow the recommendations of the governments. Methods : We identified relevant articles to date using a manual library search, journal publications on the subject, and critically reviewed them. Results : We critically...
Topics: Coronavirus Disease, COVID-19, Health Professionals, Health Policy, Social Media, Twitter,...
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Topics: Telemedicine, COVID-19, Children, Pediatrics, Neurology
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Worm infestation issue is a common health condition observed mostly in Asian countries. The prevalence of worms in children is higher due to the habit of playing in mud or outdoors which is not found in the case of an infant. Very rarely worm infestation is observed in infants. There is a need for an investigation to be carried out for live worms in the stool. Sometimes the change in the diet of the infant, irregular bowel movements, and worm-like things in stool makes an alarming situation. We...
Topics: Worm, Infant, Banana fibers, Stool
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The Objective Structured Clinical Examination (OSCE) is considered a gold standard summative and formative assessment method wherein it is a comprehensive and standardized tool assessing the clinical competencies including psychomotor domain, attitudes, and behaviors that will be manifested in the real work of the medical graduates. Therefore, the implementation of OSCE depends on the design of a blueprint that consists of two axes; the first axis is the tested competencies according to the...
Topics: Objective structured clinical examination, Educational assessment, Medical education, Clinical...
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Simulation-Based Learning is considered the best alternative teaching and assessment tool that able to make the change in education, training, improving the quality and assessing the performance of the medical students. It helps students for acquiring many skills such as professionalism, communication, self-evaluation, time management, and teamwork. In addition, the use of simulation in medical education is based on many noble goals and ethical rules; it provides the best standards for patient...
Topics: Simulation, Obstacles, Challenges, Medical Education
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In the 1960s, Jeff Watkins and colleagues discovered N-methyl-d-aspartate (NMDA) receptors, and since then, it has been a pharmacodynamic target for many neurological and psychiatric drugs. NMDA is a glutamate receptor and ion channel protein located in nerve cells. There are many subunits for the NMDA receptor. They are all working together in a harmonic pattern to regulate the calcium permeability and the voltage-dependent sensitivity to magnesium influenced by the binding of glutamate as a...
Topics: Neuropathology, Psychiatry, Pharmacology
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Introduction : This study was conducted to assess the traditional beliefs and practices in postpartum care among Indonesian and Filipino mothers to propose a program to improve maternal and child health. Methods : The study utilized a descriptive research design to Indonesian mother respondents (n=110) and Filipino mother-respondents (n=119) who were conveniently selected. Traditional beliefs focused on technological factors, religious and philosophical factors, kinship and social factors,...
Topics: Traditional, Culture, Postnatal care, Cultural diversity, Indonesia, Philippines
Introduction : Tuberculosis infection caused by Mycobacterium tuberculosis is one of the most common infectious diseases, especially in countries such as Iran. The course of treatment and the number of drugs used vary depending on the severity of the disease and the parts of the body involved. The resistant tuberculosis to treatment has increased in recent years. Thus, this study was conducted to investigate the frequency distribution of response to treatment of patients with tuberculosis in...
Topics: Mycobacterium tuberculosis, Resistant tuberculosis, Treatment
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Introduction : Pressure ulcers (PU) are a major health problem, causing increased health costs as well as workload of health workers. In this study, we aimed to analyze the developments in PUs and to add perspective to future studies by examining the research articles published on PUs, which is an increasing health problem worldwide. Material and methods : Bibliometric analysis method was used in this study. The data was obtained by searching the Elsevier Scopus database with using the keywords...
Topics: Pressure ulcers, Bibliometric method, Scopus database
During December 2019, a rapid increase in the number of SARS-CoV-2 (COVID-19) cases was reported worldwide. We investigated several factors for rapid increase in SARS-COV-2. Genomic sequence reveals that domestic and wild animals were likely ancestors and zoonotic source for SARS-CoVs, MERS-CoVs, and SARS-CoV-2; these viruses replicated in animals and humans during past several decades, exhibiting diverse mutations and self-limiting diseases except during outbreaks. SARS-CoV-2 has been...
Topics: SARS-CoV-2, RT-PCR, Antibody, Zoonotic, Animal transmission, Genomics, Asymptomatic fraction, Herd...
Introduction : In mechanically ventilated patients, ventilator-associated pneumonia (VAP) is a major cause of prolonged hospitalization with increased morbidity and mortality. There is a lack of studies on the relationship between bacterial colonization of the ventilator circuit (VC) and VAP. This study aimed to investigate the role of bacterial colonization of VC in the development of VAP and identify antibiotic susceptibility trends for isolated strains. Methods : A prospective study of the...
Topics: Ventilator circuit, Bacterial colonization, Antibiotic resistance, Intensive care unit
Introduction : Alternating and pulsed electromagnetic magnetic fields (AEMF and PEMF) of different amplitudes and frequencies can induce metabolic and proliferative effects in osteoblasts, but there is no clearly directed tendency of these effects. I hypothesize that there are extremely low triggering parameters of alternating electromagnetic field (EMF) intensity, i.e., above the background magnetic field on earth but below the lowest AEMF and PEMF that have been investigated to date (above...
Topics: Cell maturation, Cell proliferation, Electromagnetic field, Osteoblast, PEMF
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Central precocious puberty (CPP) is a rare disease. The mean annual incidence in girls is 0.8-1.1/100,000 and in boys 0-0.1/100,000. Intracranial arachnoid cysts (ICACs) are usually congenital and represent 1% of intracranial masses in newborns. Intraventricular location is rare. The objective of this work is to carry out a literature updated review of the coexistence of CPP and intraventricular arachnoid cyst (IVAC). ICACs are usually asymptomatic but can present with CPP in 10-40% of...
Topics: Central precocious puberty, Intraventricular arachnoid cyst, Children, Rare diseases, GnRH test,...
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Introduction : Diabetes mellitus is a chronic metabolic disorder that induces elevated plasma glucose levels. Diabetic patients are more susceptible to infections, especially fungal infections. There is a direct relationship between increased blood glucose levels and the number of Candida hyphae in the oral mucosa. This study aimed to evaluate oral candidiasis and the different Candida species found in patients with and without diabetes mellitus. Methods : A search for studies on oral...
Topics: Blood glucose, Oral candidiasis, Diabetes mellitus, Risk factors
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The outbreak of novel Coronavirus disease 2019 (COVID-19) has emerged as a global pandemic and a public health crisis. COVID-19 is the clinical manifestation of infection with Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2). Although it is predominantly a respiratory illness, there is growing awareness of the cardiovascular manifestations of COVID-19 disease. Patients with pre-existing cardiovascular co-morbidities appear to be at highest risk for mortality from this disease along...
Topics: COVID-19, SARS-CoV-2, Myocarditis, Heart failure, Arrhythmia
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Introduction : Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) is spreading rapidly around the world caused serious respiratory disease leading to death, therefore vaccine is the effective way to control this pandemic. Scientists tried to produce safe and effective SARS-CoV-2 vaccines in record time and vaccination program started in December 2020. The aim of this study to determine the impact of SARS-CoV-2 vaccine on COVID-19 disease. Materials and methods : The COVID-19 cases...
Topics: Full vaccine, Total vaccine, COVID-19, SARS-CoV-2, mRNA vaccine, Vector vaccine, Inactivated virus...
Introduction : During COVID-19 pandemic, when social distancing becomes compulsory for all, a nation-wide school closure was implemented. The aim of this paper is to assess the impact of COVID-19 lockdown on children with ASD and their families in Tripoli, Libya. Materials and Methods : We conducted face-to-face interviews with parents of children with Autism Spectrum Disorder (ASD) during the period of the outbreak between June to December 2020. The Modified Check list of Autism in Toddlers...
Topics: Autism, COVID-19, Behaviour, Lockdown, Libya
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After spillover from Wuhan (China) in December, 2019, SARS-CoV-2 related respiratory disease (COVID-19) has rapidly affected all countries. The pandemic has posed a serious threat to world health resources. At present, there is no recommended treatment or vaccine for SARS-CoV-2. However, various drug combinations are under trial. Reversion to general principles of prevention is the preferred strategy under such circumstances. We discuss the importance of wearing a face mask and present a...
Topics: COVID-19, SARS-CoV-2, Face mask, Pandemic, Protection
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Introduction : Face masks use among Cameroonians is a new behavior. Many citizens have adopted face masks as a step to prevent the spread of COVID-19. Individuals might use face masks because of their profession, risk perception, and social status. This study aims at evaluating the relation between occupation and face masks use in COVID-19 setting in Cameroon. Our study hypothesizes that face masks use is not associated with occupation in Cameroon. Methods : A survey was conducted from May 13...
Topics: Face masks, Coronavirus, Cameroon, COVID-19, Occupation, Behavior, Health professionals
This case report presents a lipofibromatous hamartoma of the median nerve in a 31-year-old man who presents local deformity and a sensory deficit in the nerve territory. The tumor was evaluated with magnetic resonance, computed tomography, and plain film radiography, studying the pathognomonic findings of this tumor. The patient did not want surgical treatment because of prior surgical sequelae. A prior surgical biopsy was reported as a peripheral nerve with normal axonal fascicles surrounded...
Topics: Lipofibromatous hamartoma, Median nerve, Carpal tunnel, Magnetic resonance, Macrodactyly
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Melkersson-Rosenthal syndrome (MRS) is a rare neuromucocutaneous granulomatous disorder classically defined by the triad: fissured tongue (lingua plicata), recurrent orofacial edema, and relapsing facial paralysis. Association with other dysimmune disorders was reported suggesting an immunological origin to this syndrome. The association with autoimmune thyroiditis remains exceptional and unusual. We report the original case of an MRS associated with Hashimoto autoimmune thyroiditis in a...
Topics: Melkerson-Rosenthal syndrome, Autoimmune thyroiditis, Hashimoto thyroiditis, Lingua plicata
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We report a case of a 25-year-old male with a long history of watering from both the eyes. Complete ocular examination of the patient was carried out under slit lamp. Out of four, three punctums were found absent in our patient. Our case highlights a rare case of epiphora from both the eyes.
Topics: Punctum, Agenesis, Watering
Introduction : SARS-CoV-2 continues to raise health and socio-economical concerns globally. The recent discovery of the B.1.1.529 (Omicron) variant with its critical mutations has heightened the debate about the need for a better global vaccination rollout to prevent the emergence of new SARS-CoV-2 strains. Optimizing vaccine rollout in Africa is crucial for the management of the pandemic and preventing the rise of new strains. To better direct efforts and interventions it is important to know...
Topics: SARS-CoV-2, Africa, COVID-19, Vaccine, Immunology, New strains, International relations
Background: In cases of respiratory failure, Lung-Protective Ventilation Strategy (LPVS) which limits ventilator-induced lung injury is recommended. However, CO2 retention is a major impediment for LPVS and Extracorporeal membrane oxygenation (ECMO) supplies enough time to the lungs for rest and recovery. We aimed to find out the connection between ECMO usage and the reduction of mechanical ventilatory values in patients who required ECMO therapy after cardiac surgery due to pulmonary failure....
Topics: Extracorporeal membrane oxygenation, Lung-protective ventilation strategy, Cardiovascular surgery
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Introduction : Medicinal plants have been the most productive source of leads for the development of drugs from ancient times. Current research in drug discovery involves a multifaceted approach combining botanical, biological, and molecular techniques. Medicinal plant based drug discovery continues to provide novel and important leads against several diseases. Methods : Relevant articles relating to the concept were identified using a combination of manual library search as well as journal...
Topics: Medicinal plants, Coronavirus, Diseases, Health, Traditional medicine
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Topics: COVID-19, Coronavirus, Corona outbreaks, Corona pandemics, Vitamin-D deficiency, Vitamin-D...
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Introduction : Susceptibility to some infectious diseases has been associated with blood group phenotypes. Coronavirus disease 2019 (COVID-19) is a new infectious disease caused by a novel corona virus designated Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) which has spread rapidly around the world. The objective of this study was to determine if the susceptibility or severity to COVID-19 was associated with ABO blood group distribution among the affected countries. Materials...
Topics: ABO blood group, COVID-19, SARS-CoV-2
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Topics: SARS-CoV-2, Diagnosis, Hygiene
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Introduction : There is the obscurity of published data on surgical management of external abdominal wall hernias in our environment. This study was, therefore, to describe the pattern, outcome, and experience in the surgical management of anterior abdominal wall hernias in Shisong, Cameroon. Methods : This was a descriptive retrospective study conducted at St. Elizabeth Catholic General Hospital, Shisong. The various cases of abdominal wall hernias performed in the hospital during the study...
Topics: Herniotomy, Hernioplasty, Inguinal hernia, Incisional hernia, Ventral hernia, Spigelian hernia
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Introduction : With the increase of COVID-19 cases, an unusual manifestation for this type of virus began to appear anosmia and dysgeusia, which could indicate a neurologic alteration. In this context, it seems likely that subclinical manifestations of baroreflex involvement occur. The vegetative nervous system carries out the regulation of the baroreflex through the balance between sympathetic and parasympathetic activity. The objective of this study is to verify whether patients with COVID-19...
Topics: Dysautonomia, COVID-19, Heart rate variability
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Acute mesenteric lymphadenitis (AML) remains unusual during systemic lupus erythematosus (SLE), and only a few sporadic observations have been found in the medical literature. It may exceptionally be the first manifestation revealing SLE representing a real diagnostic and therapeutic challenge for clinicians (specific lupus manifestation or infectious complication?). We report an original observation of isolated AML revealing SLE in a 29-year-old Tunisian woman without pathological medical...
Topics: Acute mesenteric lymphadenitis, Systemic lupus erythematosus, Lymphadenitis, Mesenteric adenitis
Introduction : Urinary tract infections (UTI) are one of the most common human bacterial infections encountered by physicians. The risk of resistant microbes is emerging as a result of the overuse of antibiotics treatments. The presence of pathogens with increased resistance to antimicrobial agents makes UTIs difficult to treat. This study was aimed at determining the prevalence of the pathogens that cause UTIs, as well as the antibiotic susceptibility of these isolates. Materials and methods :...
Topics: Antibiotic resistance pattern, Urinary tract infection, Urine culture
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Recently, an upsurge in the incidence of several emerging infectious diseases is causing great challenges to the health professionals throughout the globe. Since early 2020, an outbreak of coronavirus disease 2019 (COVID-19), now a pandemic, is hitting the world severely. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causative agent of COVID-19, gain entry through the respiratory systems (nasopharyngeal) route causing infection. This disease is reported from all continents...
Topics: Coronavirus, COVID-19, Emerging infectious disease, Public health, RT-PCR, SARS-CoV-2
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Introduction : There is much lack of knowledge concerning most prostatic malfunction, especially the reasons and detailed nature of its pathologies. In spite of advances in medical science, the differential diagnosis of prostatic pathologies has steadily increased in complexity and controversy. A proposal has been made that prostatic calcium (Ca) content determinations may aid in resolving these issues for prostate disorders and especially as an indicator of its carcinoma risk. As a result many...
Topics: Calcium, Human prostate, Normal prostatic tissue, Biomarkers
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The present world has observed the SARS-CoV2 or COVID-19 spreading rapidly with a rising death toll and transmission rates with an absence of proper data management and information sharing. The current traditional database storage system has the limitations of a centralized control system and tampering of data, particularly when it is being shared with others. The Novel technology known as “Blockchain” is a distributed ledger technology that acts as a shared database, keeping all its copies...
Topics: COVID-19, Blockchain, Pandemic, Novel coronavirus, Database, Epidemic
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Hypoxemia is defined as the decrease in arterial partial pressure of oxygen (PaO2) below 80 mmHg. One of the ways to alleviate this condition is through oxygen therapy, which consists of administering oxygen at a concentration higher than atmospheric. This therapy is indicated in various pathologies and is aimed to treat hypoxemia and reduce the patient's myocardial demand and respiratory effort. Classically, this treatment has been carried out using low-flow systems, in which the inspiratory...
Topics: Respiratory insufficiency, Oxygen therapy, High flow oxygen therapy
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Introduction : Oral and dental (OD) disorders in children with Rubinstein-Taybi syndrome (RTS) are frequent but not well-known by dentists and pediatricians due to the syndrome being extremely rare. Objective : To describe the OD findings observed in a 5-year-old girl with RTS and to update the literature. Clinical case : The patient presented the following OD manifestations: prominent lower lip, narrow mouth opening, narrow and arched palate, history of angular cheilitis, micrognathia, poor...
Topics: Rubinstein-Taybi syndrome, Odontostomatology disorders, Pediatric dentistry, Disabled persons,...
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Introduction : The relationship between inflammation and cancer has long been the focus of researchers' interest. There are many inflammatory markers studied for this purpose in the literature. In this context, we focused on the effects of platelet counts and platelet mass index (PMI) as inflammatory markers in the diagnosis of low-volume localized testicular cancer. Materials and methods : Thirty-eight patients with localized testicular cancer with a mean age of 30.84 ± 5.79 years and 38...
Topics: PMI, Testicular tumours, Biomarkers
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Peripartum cardiomyopathy (PPCM) is a rare but life-threatening condition defined by left ventricular dysfunction and heart failure (HF), occurring in late pregnancy or, more commonly, the early postpartum period. In African American women, women with pre-eclampsia, advanced maternal age, and numerous gestation pregnancies, there is a greater incidence. Although the pathophysiology of PPCM is still undetermined, the importance of vasculo-hormonal pathways has been suggested in research over the...
Topics: Cardiomiopathy, Heart failure, Pre-eclampsia, Pregnancy
Introduction : Early, high-quality cardiopulmonary resuscitation (CPR) increases survival rates in cardiac arrest. Although most cases occur at home and are witnessed, CPR is performed in few of these cases. For this reason, teaching CPR is especially important in relatives of patients with high cardiovascular risk. Therefore, the aim of this study was to demonstrate the effectiveness of the Family and Friends CPR course in the theoretical and practical learning of cardiopulmonary resuscitation...
Topics: Cardiopulmonary resuscitation, Cardiac arrest, Learning, Relatives, Cardiovascular diseases
Background : In recent years, due to the inappropriate use of antibiotics, drug resistance has increased in gram negative bacilli, including Klebsiella pneumoniae. Drug resistance is associated with an increase in mortality and therapeutic costs. Therefore, determination of an antibiotic resistance pattern for choosing the appropriate treatment for infections caused by this bacterium seems necessary. This study was conducted to determine the antibiotic resistance pattern of Klebsiella...
Topics: Klebsiella, Resistance, Antibiotic
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The promotion of student engagement in simulation-based learning depends on authenticity, fidelity, and realism. Moulage is a simulation of illnesses or physical signs onto standardized patient or manikin via using makeup techniques or other elements acting as visual and tactile cues to promote learner engagement through more real-world experience. Therefore, moulage may be used broadly in medical education wherein its authenticity helps to improve the learning outcomes and performance of...
Topics: Simulation, Moulage, Medical Education
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Introduction : We held a class for supporters in dementia prevention to nurture people who can carry out activities that prevent dementia and restrict its advancement. The objective was for enrollees who have completed the class to be able to visit the homes of older adults who have difficulty leaving their homes and help them carry out activities that prevent dementia. The trained supporters then evaluated the cognitive and psychological effects of interaction. Method : The participants were...
Topics: Dementia prevention, Supporters, Visit the homes, Conversation
Introduction : Successful medical decisions are highly reliant on medical laboratory results; as such, laboratory results are essential to patient health management, and errors in those results may lead to serious complications and death. The aim of the present study was to assess the knowledge of medical laboratory practitioners in Saudi Arabia regarding factors that may influence medical laboratory testing results and the correct actions for troubleshooting. Methods : A total of 256...
Topics: Knowledge, Attitudes, Medical laboratory professionals, Non-pathological factors
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Introduction : We report a case of gastroschisis seen in our center, highlighting the rarity of this clinical entity. The author equally reviewed the existing literature covering the epidemiology, etiopathogenesis, management options, and outcomes of gastroschisis in low-income countries in sub-Saharan Africa and compares the reports with middle-income and high-income countries across the world. Case presentation : A preterm female neonate with a clinical diagnosis of gastroschisis at a primary...
Topics: Gastroschisis, Congenital anomaly, Anterior abdominal wall defects, Low-resource setting
Antibiotic resistance is a significant issue for the medical community, worldwide. Many bacteria develop drug resistance by utilizing multidrug resistant or MDR efflux pumps that can export antibiotics from bacterial cells. Antibiotics are expelled from bacteria by efflux pumps a part of the resistance nodulation division (RND) family. Types of RND efflux pumps include the AcrAB-TolC tripartite protein pump. There are an excessive number of antibiotic compounds that have been discovered;...
Topics: Efflux pump, Antibiotic resistance, Bacterial metabolic pathways
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Retinitis pigmentosa (RP) or hereditary retinal dystrophy is a rare disease that can be isolated (non-syndromic RP) or associated with other systemic signs (syndromic RP). Kidney damage is exceptionally reported in patients with RP, particularly in syndromic forms. Association with renal amyloidosis remains unusual with only one reported case of RP and hereditary gelsolin amyloidosis due to a G654A gelsolin mutation defining the new syndrome of Ardalan-Shoja-Kiuru. Apart from this publication,...
Topics: Retinitis pigmentosa, Light chain amyloidosis, AL amyloidosis, Primary amyloidosis
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ntroduction : The antimicrobial agents have saved human from several infectious disease. However, bacteria have capability to develop to become resistant to antibiotics and incorrect use of antibiotics is the main determinants of development of antimicrobial resistance which is a public health issue. Attention on medical students and community people should be emphasized by both education and promotion. Thus, this study was aimed to assess the present knowledge, attitude and behavior of Libyan...
Topics: Antibiotics, Bacteria, Community, Health education, Libya, Utilization, Students
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Topics: Hospital Pharmacist, Professional Skills, Emergency Department
Introduction : Biomechanical stimulation of cultured human osteoblast-like cells, which is based on controlled mechanical vibration, has been previously indicated, but the exact mechanical parameters that are effective for cells' proliferation enhancement are still elusive due to the lack of direct data recordings from the stimulated cells in culture. Therefore, we developed a low friction tunable system that enables recording of a narrow range of mechanical parameters, above the infrasonic...
Topics: Osteoblast, Mechanical stimulation, Vibration, Mechanotransduction
Introduction : There are very few studies on the effects of regular blood transfusions on the hemodynamic organization of patients with Beta-Thalassemia Major (BTM). Ambulatory Blood Pressure Monitoring is method that evaluates fluctuations in day-night periods and life cycle changes. In this study, we aimed to investigate the effects of blood transfusion on hemodynamic parameters by the Ambulatory Blood Pressure Monitoring method on the day of transfusion in patients with a diagnosis of...
Topics: Non-dipper, Thalassemia, Transfusion, Blood pressure
Introduction : The hand harbors different species of bacteria that may play a role in the transmission of infectious diseases. Therefore, this study was conducted to determine the bacterial profile of hands and assess the efficacy of the three most common methods of hand cleansing on the reduction of that bacteria. Materials and methods : Hand swaps were collected from 150 adults. The identity of bacteria was done by standard microbiological procedures. Each participant applied one of three...
Topics: Hand hygiene, Handwashing, Sanitizer, Hand wipes
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Introduction : Aspirin has justifiably been called the first miracle drug. In this article, we highlight the history of Aspirin, a novel mechanism of action, and its use in cardiovascular and other diseases. Also included is a brief statement of emerging new applications. Objective : We highlight principal mechanisms by which Aspirin inhibits acute inflammation and alters platelet-biology; therefore, hypothesized that Aspirin might prove highly beneficial as a novel therapeutic drug for...
Topics: Aspirin, COVID-19, Systemic inflammatory response, Cytokine storm, Nonsteroidal antiinflammatory...
Editorial
Topics: Emergency, Primary Care, Medicine
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Introduction : Coronavirus disease 2019 is the recent most devastating global outbreak that influenced humanity in the new millennium since decades from the last devastating pandemic. Despite being of low mortality rates - if compared with the previous epidemics in human history - the progressively spreading epidemic does not impact health and life but also has changed man's lifestyle, economy, politics and many other undisputed admitted daily routines. Methods : The present case provides...
Topics: CoVID-19, Pandemic, Polynomial regression, PHEIC
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Aluminum phosphide (ALP) is a highly toxic compound most commonly available as Celphos in Nepal. Suicidal ingestion is common in developing countries like Nepal as it is easily available and has a high mortality rate. Farmers to protect crops from rodents and pests use it. Here we present a case of a 24-year-old female with suicidal ingestion of one and a half-tablet of ALP presented with abdominal pain and vomiting. The patient developed metabolic acidosis, hyperkalemia, acute respiratory...
Topics: Aluminum phosphide, Suicidal ingestion, Metabolic acidosis, Acute respiratory distress, Magnesium...
Persistent urogenital sinus (PUGS) is an uncommon developmental cloacal anomaly, with Incidence of 0.6 in 10000 female births. Herein we depict the case of a 22-year of age lady who presented with Infertility for 16 months with dyspareunia and was found to have Persistent urogenital sinus associated with other urogenital anomalies as unilateral rudimentary horn with ipsilateral renal agenesis and contralateral dermoid cyst. The patient was successfully treated with the excision of the sinus,...
Topics: Urogenital sinus, Renal agenesis, Rudimentary horn
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Introduction : Amyand’s hernia is an extremely rare and atypical hernia that is difficult to diagnose clinically characterized by the herniation of the appendix into the inguinal sac. The aim of this report is to describe a case of Amyand’s hernia and highlights the importance of early CT scanning in reaching the exact and early diagnosis of Amyand’s hernia. Case report : We present a rare case of a 69-year-old female patient with a history of intermittent pain in the right inguinal...
Topics: Amyand’s hernia, Inguinal hernia, Appendix, Hernia sac, CT, Appendectomy
Iberoamerican Journal of Medicine
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Introduction : Recent advances in nanotechnology have introduced new therapeutic materials for periodontal therapy. Previous studies showed that nanoparticles of silver provide high antibacterial activity. Taking this in consideration, it can be used in nonsurgical periodontal therapy. The present study focuses on efficacy of subgingival local drug delivery of silver nanoparticles in comparison with tetracycline in chronic periodontitis. Methods : To understand the effect of silver...
Topics: Silver nanoparticles, Periodontitis, Chronic periodontitis
Iberoamerican Journal of Medicine
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Topics: Blood pressure, Atherothrombotic syndrome, Circadian rhythm
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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NAD(P)H:quinone oxidoreductase 1 (NQO1) is considered as one of the most significant enzyme in cellular defense due to its ability to detoxify reactive quinones and quinone imines to their less toxic hydroquinones forms. NQO1 is a xenobiotic metabolizing cytosolic enzyme that catalyzes the reduction of two- or four-electron of numerous exogenous and endogenous quinones by utilizing flavin adenine dinucleotide (FAD) as a cofactor. NQO1 enzyme exists as a homodimer enzyme and is biochemically...
Topics: Gene expression, NQO1, Keap1, ARE
The COVID-19 pandemic and the limited therapeutic arsenal available strain daily clinical practice. Guidelines have recently recommended routine anticoagulation of hospitalized COVID-19 patients. However, apart from the expert panels’ experience, the provenance of this recommendation is not clear, due to the scarce published evidence. We provide a narrative review with the objective of unraveling the rationale for this practice. First, we analyze the biochemical, histopathological and...
Topics: COVID-19, SARS-CoV-2, Thrombosis, Anticoagulation
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Vesiculobullous lesions can be developed by less than 5% of patients with systemic lupus erythematosus (SLE). Among these lesions, bullous systemic lupus erythematosus (BSLE) is one of the rarest and most challenging cutaneous presentations of the disease. Its frequency in the largest series of 5149 patients with cutaneous lupus was 0.19%, and the majority of cases are reported as sporadic observation or small series not exceeding ten cases. We report the original observation of BSLE revealing...
Topics: Bullous systemic lupus erythematosus, Cutaneous lupus, Systemic lupus erythematosus, Skin
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Introduction : Over the past 10 years, much attention has been paid to the development of new antiviral drugs based on the suppression of the proteolytic activity of enzymes by trypsin inhibitors of plant and animal origin. Material and methods : We used a trypsin inhibitor from barley, trielin- (isolated by employees of the Agro-Industrial Institute of Selection and Genetics of the Ukrainian Academy of Sciences from the salivary glands of a dog); ovomukoid (isolated from duck eggs by employees...
Topics: Influenza virus, Tripsin-like proteinase, Inhibitor
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Introduction : World Health Organization declared COVID-19 as a pandemic, and like any global health crisis at its beginning, need a commitment to take the necessary precautions due to its spread among people before and during the presence of vaccine or drug. This study aims to assess public opinion and practice of Libyan community in the context of the COVID-19 pandemic. Materials and methods : A cross-sectional online study was conducted among Libyans between Sep. 15th, and Oct. 29th, 2020...
Topics: Awareness, Coronavirus, COVID-19, Libyan people, Practice
Iberoamerican Journal of Medicine
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Topics: Pseudo prune belly syndrome, Abdominal wall laxity, Female
Iberoamerican Journal of Medicine
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Introduction : Stroke is defined as sudden onset of focal neurological deficit lasting more than 24 hours duration. There are several complications derived from these illness, including neurological disorders like gait dysfunction. Attending to this problem, some treatments have been developed, including ankle foot orthosis (AFO), knee gaiter and bobath intervention. The aim of this study is to compare the efficacy of functional task in patients affected by stroke. Material and Methods : Timed...
Topics: Functional Task, Bobath, Knee Gaiter, Gait dysfunction, Stroke
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Introduction : Although infective endocarditis (IE) is rare disease, this disease has importance due to its high morbidity and mortality rates. The exact incidence is not known as it is not a reportable disease. Unlike developed countries, the disease affects the young more than the elderly in developing countries. Most of the time, the diagnosis cannot be made at the first examination and the disease is often overlooked. In order to reduce the mortality and morbidity of this disease, it is...
Topics: Infective endocarditis, Bibliometric analysis, Scopus database
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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Introduction : The spleen is located in the upper part of the abdominal cavity. As an organ, the spleen can have various shapes and size. Material and methods : The human spleen was studied in 273 cadavers (154 men and 119 women) who did not have diseases of the spleen. The shape of the spleen was analyzed based on splenic index, Michels classification. Results : The most common shape of the spleen in men is the elongated one. It was encountered in 79 (51.3%) cases out of 154. In women, the...
Topics: Spleen, Splenic shape, Dissection, Anatomy
Introduction : Public health security is concerned with infection prevention and control worldwide. These measures are the concern of all and sundry to ensure prevention of any outbreaks of diseases that has epidemic potential. Africa may be uniquely positioned to have the most severe and under-detected outcomes related to COVID-19 infection. This article seeks to highlight such challenges of healthcare delivery systems in the context of the COVID-19 pandemic in sub-Saharan Africa. The...
Topics: COVID-19, Preparedness, SARS-CoV-2, Resource-Constrained Settings, HealthCare Systems, Sub-Saharian...
Iberoamerican Journal of Medicine
by Iberoamerican Journal of Medicine
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The relationship between the intra-abdominal pressure (IAP) and intracranial pressure (ICP) has been suspected for more than 100 years and was subsequently confirmed by numerous studies in both animals and humans which demonstrate the link and the positive correlation between IAP and ICP. There are mounting concerns that the pneumoperitoneum created during laparoscopic surgery to create space for instrument placement and to allow safe tissue dissection may result in an increase in the ICP...
Topics: Laparoscopy, Surgery, Ventriculoperitoneal shunts, Safety
Iberoamerican Journal of Medicine
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Topics: Coronavirus, COVID-19, Pandemic
Iberoamerican Journal of Medicine
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World Health Organization (WHO) is gathering the latest scientific findings and knowledge on coronavirus disease (SARS-CoV-2) and compiling it in a database. WHO update the database daily from searches of bibliographic databases, hand searches of the table of contents of relevant journals, and the addition of other relevant scientific articles that come to our attention. The entries in the database may not be exhaustive and new research will be added regularly. Nobel coronavirus investigators,...
Topics: SARS-CoV-2, Coronavirus, Antivirals